Cannabis sativa

                                                    Cannabis sativa


       Cannabis (Cannabis sativa) is an herbal drug. It contains chemicals called cannabinoids, including delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD).


The cannabinoids in cannabis work by binding to specific sites in the brain and on the nerves. There are over 100 cannabinoids in cannabis, but THC and CBD are the most well-studied. Cannabinoids are found in the highest levels in the leaves and flowers of the plant.

Cannabis is commonly used as a recreational drug. People also commonly use cannabis for multiple sclerosis (MS) and nerve pain. It is also used for nausea, vomitingmigraine, and many other conditions, but there is no good scientific evidence to support these uses. There is also no good evidence to support using cannabis for COVID-19.

Don't confuse cannabis with hemp. Hemp contains very low levels of THC, less than 0.3% according to legal standards. Both hemp and cannabis also contain cannabinoids such as CBD, cannabidivarin (CBDV), cannabigerol (CBG), and others. Unlike hemp, cannabis is illegal under federal law in the US. It is classified as a Schedule I controlled substance. But some states have legalized or decriminalized recreational use.


Cannabis sativa usage

Cannabis sativa L. has been used for medicinal purposes in many cultures for hundreds of years, for example for the treatment of pain, spasms, asthma, insomnia, depression, and loss of appetite.


Which part of Cannabis
sativa is used
When so used, preparations of flowers and fruits (called marijuana) and leaves and preparations derived from resinous extract (e.g., hashish) are consumed by smoking, vaporising, and oral ingestion.

Uses & Effectiveness

Possibly Effective for

    • Multiple sclerosis (MS). Spraying a cannabis extract spray (Sativex) under the tongue seems to improve symptoms of MS such as muscle spasms and nerve pain. This product is not available in the US. In the UK and Canada, this product is a prescription drug.
    • Nerve pain. Smoking cannabis seems to moderately reduce nerve pain caused by HIV and other conditions. The pain relief lasts for about 2 hours.
There is interest in using cannabis for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.
               Side Effects
When taken by mouth: Cannabis is possibly unsafe when used in large amounts or long-term. Edible cannabis containing 50 mg or more of THC has been linked with serious side effects. Regularly taking large amounts of cannabis might cause cannabinoid hyperemesis syndrome (CHS). CHS leads to severe nausea and vomiting that doesn't respond to typical anti-nausea drugs. Also, using cannabis for at least 1-2 weeks can cause dependence.
When sprayed into the mouth: A specific cannabis extract (Sativex) is possibly safe. This is a prescription-only product in the UK and Canada. It is not approved in the US.
When inhaled: Cannabis is possibly unsafe when used in large amounts or long-term. Smoking or vaping cannabis can cause breathing problems. Vaping products containing THC have been linked to serious lung injury. Regularly smoking cannabis may cause CHS and/or dependence.
                                               

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